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Long-term Use of Proton Pump Inhibitors Linked to Bacterial Infections, Fractures

A new study has linked long-term use of proton pump inhibitors to increased risk of headache, nausea and bacterial infections. The drugs are also linked to an increased risk of spinal and wrist fractures in postmenopausal women. There is also an increase risk of pneumonia. Proton pump inhibitors like Prilosec, Nexium and Protonix are used to reduce acid reflux.

The L.A. Times reports that the increased risk of a bacterial infection is probably because the reduction of acid makes the stomach and intestines more hospitable for becteria like C. difficile. The proton pump inhibitors can also "impair the uptake of the calcium required for strong bones."

Dr. Jennifer Ashton discusses the new study on the CBS Early Show. Take a look:



Posted on May 11, 2010





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